Human salivary alpha-amylase reactivity in a psychosocial stress paradigm
- Autor(en)
- Urs M Nater, Nicolas Rohleder, Jens Gaab, Simona Berger, Andreas Jud, Clemens Kirschbaum, Ulrike Ehlert
- Abstrakt
Biological indicators for stress reactions are valuable markers in psychophysiological research and clinical practice. Since the release of salivary enzyme alpha-amylase was reported to react to physiological and psychological stressors, we set out to investigate human salivary alpha-amylase changes employing a reliable laboratory stress protocol to investigate the reactivity of salivary alpha-amylase to a brief period of psychosocial stress. In a within-subject repeated-measures design, 24 healthy adults were exposed to the TSST and a control condition on separate days with randomized sequence. Salivary alpha-amylase, salivary cortisol and heart rate were repeatedly measured before, during and after both conditions. Significant differences between psychosocial stress and the rest condition in alpha-amylase activity [F(3.74,86.06)=4.52; P=0.003], cortisol levels [F(4.21,88.32)=12.48; P<0.001] and heart rate [F(1,22)=81.15; P<0.001] were observed, with marked increases before and after stress. The data corroborate findings from other studies that showed increased levels of alpha-amylase before and after psychological stress. We discuss the role of salivary alpha-amylase as a promising candidate for a reliable, noninvasive marker of psychosocial stress.
- Organisation(en)
- Externe Organisation(en)
- Universität Zürich (UZH)
- Journal
- International Journal of Psychophysiology
- Band
- 55
- Seiten
- 333-342
- Anzahl der Seiten
- 10
- ISSN
- 0167-8760
- DOI
- https://doi.org/10.1016/j.ijpsycho.2004.09.009
- Publikationsdatum
- 2005
- Peer-reviewed
- Ja
- ÖFOS 2012
- 501010 Klinische Psychologie
- Schlagwörter
- Sustainable Development Goals
- SDG 3 – Gesundheit und Wohlergehen
- Link zum Portal
- https://ucris.univie.ac.at/portal/de/publications/human-salivary-alphaamylase-reactivity-in-a-psychosocial-stress-paradigm(c3c5fd13-3917-4c97-9114-062a77620396).html