Determinants of salivary alpha-amylase in humans and methodological considerations

Autor(en)
Nicolas Rohleder, Urs Markus Nater
Abstrakt

Salivary alpha-amylase (sAA) has been proposed as a marker for activity of the sympathetic nervous system (SNS). Recent studies in support of this hypothesis have led to an increased number of researchers integrating amylase measurements into their study designs. Salivary alpha-amylase is produced locally in the salivary glands, controlled by the autonomic nervous system. This entails some methodological consequences and potential pitfalls that might lead to increased error variance and thus prevent successful testing of hypotheses. The goal of this review is to summarize basic and recent findings on methodological issues and potential factors influencing sAA measurement, and to derive a set of recommendations enabling researchers to successfully using sAA in psychoneuroendocrinological experiments.

Organisation(en)
Externe Organisation(en)
Brandeis University, Universität Zürich (UZH)
Journal
Psychoneuroendocrinology
Band
34
Seiten
469-485
Anzahl der Seiten
17
ISSN
0306-4530
DOI
https://doi.org/10.1016/j.psyneuen.2008.12.004
Publikationsdatum
2009
Peer-reviewed
Ja
ÖFOS 2012
501010 Klinische Psychologie
Schlagwörter
Link zum Portal
https://ucrisportal.univie.ac.at/de/publications/abc3cbd4-50ae-45f6-b8f0-136ab2907a9f