Salivary alpha-amylase as a non-invasive biomarker for the sympathetic nervous system

Autor(en)
Urs Markus Nater, Nicolas Rohleder
Abstrakt

Development of new biomarkers is a constantly evolving field of research endeavor in psychoneuroendocrinology. Salivary biomarkers have received special attention since they are readily accessible and easily obtained. Salivary alpha-amylase (sAA) has been proposed as a sensitive biomarker for stress-related changes in the body that reflect the activity of the sympathetic nervous system (SNS), and a growing body of research is accumulating to support the validity and reliability of this parameter. However, questions remain to be answered before sAA can be accepted as an index of SNS activity. This review describes sAA as an emerging biomarker for stress and provides an overview of the current literature on stress-related alterations in sAA. It critically discusses how sAA might reflect changes in the autonomic nervous system. Finally, current and future fields for the application of sAA measurement are outlined.

Organisation(en)
Externe Organisation(en)
Universität Zürich (UZH)
Journal
Psychoneuroendocrinology
Band
34
Seiten
486-496
Anzahl der Seiten
11
ISSN
0306-4530
DOI
https://doi.org/10.1016/j.psyneuen.2009.01.014
Publikationsdatum
2009
Peer-reviewed
Ja
ÖFOS 2012
501010 Klinische Psychologie
Schlagwörter
Link zum Portal
https://ucrisportal.univie.ac.at/de/publications/salivary-alphaamylase-as-a-noninvasive-biomarker-for-the-sympathetic-nervous-system(521cf63f-a000-40b6-933f-78284b26eb1a).html